The citric acid cycle, also known as the Krebs cycle or the tricarboxylic acid cycle, is at the center of cellular metabolism, playing a starring role in both the process of energy production and biosynthesis It finishes the sugar-breaking job started in glycolysis and fuels the production of ATP in the process
What is the main role of the citric acid cycle quizlet?
What is the main purpose of the citric acid cycle? To oxidize carbons in intermediates to CO2 and generate high-energy electron carriers (NADH and FADH2) and GTP The citric acid cycle begins with acetyl CoA
What are the two main benefits of the citric acid cycle?
The two main purposes of the citric acid cycle are: A) synthesis of citrate and gluconeogenesis B) degradation of acetyl-CoA to produce energy and to supply precursors for anabolism
What is the purpose of the citric acid cycle chegg?
Question: The purpose of the Citric Acid Cycle (Krebs Cycle) is: To produce the majority of ATP molecules from glucose oxidation
What role does the citric acid cycle play in cellular respiration?
The tricarboxylic acid (TCA) cycle, also known as the Krebs or citric acid cycle, is the main source of energy for cells and an important part of aerobic respiration The cycle harnesses the available chemical energy of acetyl coenzyme A (acetyl CoA) into the reducing power of nicotinamide adenine dinucleotide (NADH)
What is the purpose of the citric acid cycle what enters the citric acid cycle and what leaves?
The TCA cycle, also known as the citric acid cycle or Krebs cycle, occurs in the mitochondria and provides large amounts of energy in aerobic conditions by donating electrons to three NADH and one FADH (flavin adenine dinucleotide), which donate electrons to the electron transport chain, creating the proton gradient
Does the citric acid cycle release less energy than glycolysis?
CO2 is released during operation of the cycle It takes place in the mitochondrial matrix It does not operate under anaerobic conditions It releases less energy than glycolysis
What products of the citric acid cycle are needed for the electron transport chain?
The products of the electron transport chain are water and ATP A number of intermediate compounds can be diverted into the anabolism of other biochemical molecules, such as nucleic acids, non-essential amino acids, sugars, and lipids
What two major roles do the citric acid cycle and glycolysis have in common?
What two major roles do the citric acid cycle and glycolysis have in common? Energy conservation and biosynthesis 2 Match the polymeric molecules with the monomeric subunits into which they are converted before they can be oxidized to produce energy: A
Why is the citric acid cycle a cyclic pathway?
Why is the citric acid cycle a cyclic pathway rather than a linear pathway? It is easier to remove electrons and produce CO2 from compounds with three or more carbon atoms than from a two-carbon compound such as acetyl CoA
What are the key control points within the citric acid cycle?
The citric acid cycle is regulated primarily by the concentration of ATP and NADH The key control points are the enzymes isocitrate dehydrogenase and α-ketoglutarate dehydrogenase Isocitrate dehydrogenase is allosterically stimulated by ADP, which enhances the enzyme’s affinity for substrates
Why is the citric acid cycle called a cycle quizlet?
Why is the krebs cycle called a cycle? because the process starts over and over again because the citric acid is reused as the 4 carbon compound over and over again
Which electron carriers function in the citric acid cycle?
The electron carriers that function in the citric acid cycle are FADH2 and NADH
What is the primary role of the citric acid cycle in the production of ATP?
What is the primary role of the TCA cycle in the production of ATP? It produces more than 90% of ATP used by body cells
What happens if the citric acid cycle stops?
it wouldn’t function as properly and produce less ATP if not enough to start it movement of electrons from outside into the cell and H+ out
Does the citric acid cycle or the electron transport chain produce more ATP?
Electron transport chain This stage produces most of the energy ( 34 ATP molecules, compared to only 2 ATP for glycolysis and 2 ATP for Krebs cycle)
How does the citric acid cycle communicate with the electron transport chain?
The citric acid cycle is a series of chemical reactions that removes high-energy electrons and uses them in the electron transport chain to generate ATP As the electrons are passed from NADH or FADH2 down the electron transport chain, they lose energy The products of the electron transport chain are water and ATP
Why are coenzymes important in the citric acid cycle?
The citric acid cycle serves as the mitochondrial hub for the final steps in carbon skeleton oxidative catabolism for carbohydrates, amino acids, and fatty acids These reduced coenzymes contribute directly to the electron transport chain and thus to the majority of ATP production in the human body
What does the citric acid cycle directly produce in cells?
The citric acid cycle involves eight chemical reactions that produce carbon dioxide, ATP, NADH and FADH2 The NADH and FADH2 are electron carriers that can be used by the electron transport chain (ETC)
What is the function of glycolysis and the citric acid cycle?
Glycolysis produces the molecules that are processed by the citric acid cycle The citric acid cycle occurs in the mitochondria of the cell and will eventually break pyruvate all the way down to inorganic substances like carbon dioxide and water, thus releasing all of the energy inside the molecule
What happens between glycolysis and the citric acid cycle?
The link between glycolysis and the citric acid cycle is the oxidative decarboxylation of pyruvate to form acetyl CoA In eukaryotes, this reaction and those of the cycle take place inside mitochondria, in contrast with glycolysis, which takes place in the cytosol
What type of feedback regulates the citric acid cycle?
Electron Transport Chain Summary of Feedback Controls in Cellular Respiration Pathway Enzyme affected Effect on pathway activity citric acid cycle isocitrate dehydrogenase increase decrease α-ketoglutarate dehydrogenase increase
What needs to happen before starting the citric acid cycle?
Prior to the start of the first step, pyruvate oxidation must occur Then, the first step of the cycle begins: This is a condensation step, combining the two-carbon acetyl group with a four-carbon oxaloacetate molecule to form a six-carbon molecule of citrate
Where does the citric acid cycle happen?
In eukaryotes, the reactions of the citric acid cycle take place inside mitochondria, in contrast with those of glycolysis, which take place in the cytosol (Figure 171)
Which are formed during one turn of the citric acid cycle?
The eight steps of the citric acid cycle are a series of redox, dehydration, hydration, and decarboxylation reactions Each turn of the cycle forms one GTP or ATP as well as three NADH molecules and one FADH2 molecule, which will be used in further steps of cellular respiration to produce ATP for the cell
What are the key control points within the citric acid cycle quizlet?
Terms in this set (5) citrate synthase ATP and NADH (products) function as allosteric inhibitors; citrate and succinyl-CoA are allosteric inhibitors too isocitrate dehydrogenase α-ketoglutarate dehydrogenase complex What enzyme catalyzes the rate-limiting step of the citric acid cycle products of the Citric Acid Cycle
What are the 3 regulatory enzymes of the TCA cycle?
In eukaryotic cells TCA cycle happens in the Matrix of mitochondria In this citric acid cycle three enzymes are involved They are citrate synthase, isocitrate dehydrogenase and alpha ketoglutarate dehydrogenase